AN INVESTIGATION OF THE ANTIMICROBIAL PROPERTIES OF CHLORINE AND ALCOHOL BASED DISINFECTANTS
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- NGN 3000
Background of the study
In hospitals and other health care settings, antiseptics and disinfectants are utilized widely for a wide range of topical and hard-surface applications. In particular, they play an important role in the implementation of infection control procedures and contribute to the avoidance of nosocomial infections (Awodele , 2022). Growing worries about the possibility for microbial contamination and infection hazards in the food and general consumer markets have also led to a rise in the general public's usage of antiseptics and disinfectants. In these goods, you'll find a broad array of active chemical agents, often known as "biocides." Many of these biocides have been in use for antisepsis, disinfection, and preservation for hundreds of years or more (Bloomfield , 2022). In spite of this, far less is known about the mechanisms of action of these active medicines than is the case with antibiotics. Antibiotics typically have particular intracellular targets, but biocides may have more than one target. In general, biocides have a wider range of action than antibiotics do. Some people have hypothesized that the extensive use of antiseptic and disinfection goods may contribute to the evolution of microbial resistance, in particular crossresistance to antibiotics (Chioma , 2021).
Because of their wide range of antibacterial action, low toxicity, cheap cost, and effectiveness in biofilms, chlorinated compounds are often employed in dental clinics and laboratory environments.
1 However, they are known to cause corrosion in metals and may be rendered inactive by large amounts of organic waste. In the medical field, a chemical known as sodium dichloroisocyanurate is used; despite the fact that it is caustic, the utilization of this substance is common. Disinfectants with a slow release of chlorine dioxide incorporating corrosion inhibitors have been developed and find widespread application in industrial settings (Coogan , 2022).
There has been some research done on the possibility of using dental products that include chlorine dioxide. Studies have shown that it is effective in mouthrinses for the management of chronic atrophic candidiasis, denture stomatitis, and the control of plaque accumulation, periodontal pathogens, and oral malodor. This is because it inhibits the growth of candida albicans, which causes chronic atrophic candidiasis. 2-5 It has also been shown that sodium dichloroisocyanurate is an effective disinfectant for radiography films and irreversible hydrocolloid impression material. None of the aforementioned research, numbering six or seven, examined whether or not these disinfectants were effective against mycobacteria or the Hepatitis B virus. In addition, it has not been determined whether or not chlorine dioxide has any anti-hepatitis B viral action (Drake , 2022).
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